Table 1. The breast and lung cancer cell lines we examined are ranked by relative MUCL1 mRNA expression as determined in NextBio.com.
| Cell line | Cancer type | Fold expression change | ER/PR/HER2 status | Molecular subtype |
|---|---|---|---|---|
| KPL-4 | Breast | 269 | −/−/++ | HER2 |
| JIMT-1 | Breast | 204.1 | −/−/++ | HER2 |
| MDA-MB-361 | Breast | 174.3 | +/+/++ | LUM B |
| ZR-75-1 | Breast | 116.6 | +/+/+ | LUM B |
| MDA-MB-175-VII | Breast | 58.6 | +/−/− | LUM A |
| HCC1419 | Breast | 46.4 | −/−/++ | HER2 |
| HCC202 | Breast | 31.7 | −/−/++ | HER2 |
| BT-474 | Breast | 30.7 | −/+/++ | LUM B |
| MDA-MB-415 | Breast | 29.6 | +/−/− | LUM A |
| MDA-MB-134-VI | Breast | 14.2 | +/−/− | LUM A |
| HCC1428 | Breast | 14.1 | +/+/− | LUM A |
| HCC1954 | Breast | 12.6 | −/−/+ | HER2 |
| DU4475 | Breast | 11.3 | −/−/− | Basal |
| SK-BR-3 | Breast | 9.4 | −/−/++ | HER2 |
| ZR-75-30 | Breast | 9.3 | +/−/++ | LUM B |
| HCC70 | Breast | 6.4 | +/−/− | LUM A |
| MCF7 | Breast | 5.4 | +/+/− | LUM A |
| MDA-MB-468 | Breast | 4.0 | −/−/− | Basal |
| HCC38 | Breast | 3.7 | −/−/− | Basal |
| HCC1937 | Breast | 0.9 | −/−/− | Basal |
| NCI-H460 | Lung | 213.5 | HER2 + | Large cell |
| NCI-H520 | Lung | 150.2 | HER2 − | Squamous cell |
Abbreviations: ER, estrogen receptor; HER2, human epidermal growth factor receptor 2; MUCL1, Mucin-like 1; PR, progesterone receptor.
Fold expression change represents the level of MUCL1 in each cell line divided by the median of the gene across all normal cell lines. The ER, PR and HER2 status as well as the molecular subtype of each cancer cell line are reported.