Table 1.
Each expert's contoured GTV, pre-operative CTV and post-operative CTV sensitivity and specificity compared to the “ground truth” target volume generated by the STAPLE algorithm
| Case 1- Stage III Thymoma preop/definitive | Case 1-Stage III Thymoma postop/adjuvant | |||||
|---|---|---|---|---|---|---|
|
| ||||||
| Expert | GTV-sensitivity | GTV-specificity | CTV-sensitivity | CTV-specificity | CTV-sensitivity | CTV-specificity |
| #1 | 0.84 | >0.99 | 0.75 | >0.99 | 0.70 | >0.99 |
| #2 | 0.95 | >0.99 | 0.89 | >0.99 | 0.40 | >0.99 |
| #3 | 0.81 | >0.99 | 0.72 | >0.99 | 0.43 | >0.99 |
| #4 | 0.68 | >0.99 | 0.76 | >0.99 | 0.61 | >0.99 |
| #5 | 0.68 | >0.99 | 0.79 | >0.99 | 0.44 | >0.99 |
| #6 | 0.76 | >0.99 | 0.88 | >0.99 | 0.63 | >0.99 |
| #7 | 0.66 | >0.99 | 0.82 | >0.99 | 0.63 | >0.99 |
| Mean±SD | 0.77±0.10 | >0.99 | 0.80±0.07 | >0.99 | 0.55±0.12 | >0.99 |
GTV = gross tumor volume, CTV = clinical target volume. Staging as per the Masaoka-Koga staging system. Sensitivity and specificity values for each expert contour Warfield's simultaneous truth and performance level estimation (STAPLE) algorithm to generate a composite segmentation estimate of a “ground truth” target volume, which was then compared to each individual experts contours.