Table 3.
Sensitivity analysis; logistic regression of maternal insulin and glucose levels in subcategories of congenital heart disease for subjects with random glucose less than 200 mg/dL
| ToF vs. Controls | ||||
|---|---|---|---|---|
| Model 1 1 | Model 2 1 | |||
| Analyte | Crude OR (95%CI) | Adjusted OR (95%CI) 2 | Crude OR (95%CI) | Adjusted OR (95%CI) 2 |
| Log2(glucose) | 2.93 (0.96, 8.96) | 2.76 (0.87, 8.74) | 5.45 (1.41, 21.08) | 4.61 (1.14, 18.67) |
| Log2(Insulin) | 0.93 (0.73, 1.18) | 0.95 (0.75, 1.22) | 0.78 (0.59, 1.03) | 0.82 (0.61, 1.09) |
| dTGA vs. Controls | ||||
|---|---|---|---|---|
| Model 1 | Model 2 | |||
| Analyte | Crude OR (95%CI) | Adjusted OR (95%CI)1 | Crude OR (95%CI) | Adjusted OR (95%CI)1 |
| Log2(glucose) | 0.41 (0.10, 1.60) | 0.41 (0.10, 1.66) | 0.72 (0.16, 3.33) | 0.68 (0.15, 3.12) |
| Log2(Insulin) | 0.74 (0.55, 0.99) | 0.75 (0.56, 1.01) | 0.76 (0.55, 1.05) | 0.78 (0.56, 1.08) |
1
Model 1 shows results for glucose or insulin alone. Model 2 shows results with both analytes simultaneously evaluated
2
For all subjects, adjusting for maternal race/ethnicity (Hispanic, and White non-Hispanic) and maternal age at sample collection (continuous, in years).