TABLE 3.
Dichotomous covariates | No. of patients | DSS 5-y survival | Univariate analysis p value |
Multivariate analysis
|
|
---|---|---|---|---|---|
HR (95% CI) | p value | ||||
Sex | |||||
Male | 68 | 22.6% | NS | NA | NA |
Female | 41 | 29.3% | |||
Tobacco use | |||||
Never | 33 | 22.4% | NS | NA | NA |
Ever | 76 | 25.8% | |||
Alcohol use | |||||
Never | 30 | 32.0% | NS | NA | NA |
Ever | 79 | 20.8% | |||
Perivascular invasion | |||||
No | 52 | 17% | NS | NA | NA |
Yes | 36 | 25.5% | |||
PNI | |||||
No | 34 | 25.1% | NS | NA | NA |
Yes | 54 | 17.3% | |||
Muscle invasion | |||||
No | 101 | 27.1% | .001 | NA | NA |
Yes | 8 | 0% | |||
T classification | |||||
T1 | 22 | 50.8% | .035 | NA | NA |
T2, T3, or T4 | 86 | 19.0% | |||
ECS | |||||
Minor | 52 | 49.0% | < .001 | 3.366 (1.624–6.980) | .001 |
Major | 57 | 8.5% |
Abbreviations: DSS, disease-specific survival; HR, hazard ratio; 95% CI, 95% confidence interval; NS, not significant; NA, not applicable; PNI, perineural invasion; ECS, extracapsular spread.