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. Author manuscript; available in PMC: 2016 Aug 24.
Published in final edited form as: Head Neck. 2015 Oct 30;38(Suppl 1):E1192–E1199. doi: 10.1002/hed.24190

TABLE 3.

Dichotomous prognostic predictors of disease-specific survival for patients with extracapsular spread.

Dichotomous covariates No. of patients DSS 5-y survival Univariate analysis
p value
Multivariate analysis
HR (95% CI) p value
Sex
 Male 68 22.6% NS NA NA
 Female 41 29.3%
Tobacco use
 Never 33 22.4% NS NA NA
 Ever 76 25.8%
Alcohol use
 Never 30 32.0% NS NA NA
 Ever 79 20.8%
Perivascular invasion
 No 52 17% NS NA NA
 Yes 36 25.5%
PNI
 No 34 25.1% NS NA NA
 Yes 54 17.3%
Muscle invasion
 No 101 27.1% .001 NA NA
 Yes 8 0%
T classification
 T1 22 50.8% .035 NA NA
 T2, T3, or T4 86 19.0%
ECS
 Minor 52 49.0% < .001 3.366 (1.624–6.980) .001
 Major 57 8.5%

Abbreviations: DSS, disease-specific survival; HR, hazard ratio; 95% CI, 95% confidence interval; NS, not significant; NA, not applicable; PNI, perineural invasion; ECS, extracapsular spread.