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. Author manuscript; available in PMC: 2017 Sep 15.
Published in final edited form as: Bioorg Med Chem Lett. 2016 Jul 30;26(18):4487–4491. doi: 10.1016/j.bmcl.2016.07.071

Table 1.

Sources and counts of compounds used to explore SAR around VU0549108 and VU0624456.

Selection approach Source Number of compounds
2D similarity, VU0549108 In-house library 46
2D similarity, VU0549456 In-house library 37
VU0549456 analogs, commercial Commercial 67
Virtual screening (consensus) In-house library 237