Table 1.
Characteristics of study population
| DDLT (n=65) Mean (s.d.) or n (%) |
LDLT (n=242) Mean (s.d.) or n (%) |
p-value | |
|---|---|---|---|
| Recipient Characteristics | |||
| Recipient age | 45.7 (13.8) | 44.4 (13.1) | 0.45 |
| Female recipient | 15 (23.0%) | 77 (31.8%) | 0.17 |
| Recipient race | 0.01 | ||
| Asian | 1 (1.5%) | 5 (2.0%) | |
| African American | 6 (9.2%) | 10 (4.1%) | |
| Native American | 0 (0.0%) | 1 (0.4%) | |
| White | 47 (72.3%) | 195 (80.5%) | |
| Multiracial | 3 (4.6%) | 0 (0.0%) | |
| Unknown | 8 (12.3%) | 31 (12.8%) | |
| Recipient ethnicity | 0.002 | ||
| Hispanic/Latino | 8 (12.3%) | 6 (2.4%) | |
| Non-Hispanic/non-Latino | 43 (66.1%) | 194 (80.1%) | |
| Unknown | 14 (21.5%) | 42 (17.3%) | |
| PSC type | 0.11 | ||
| Intrahepatic | 25 (38.4%) | 127 (52.4%) | |
| Extrahepatic | 1 (1.5%) | 12 (4.9%) | |
| Intra- and extrahepatic | 36 (55.3%) | 96 (39.6%) | |
| Small duct | 2 (3.0%) | 3 (1.2%) | |
| Unknown | 1 (1.5%) | 4 (1.6%) | |
| Lab MELD at transplant | 20.2 (9.0) | 14.7 (7.2) | <0.001 |
| Inflammatory bowel disease | 0.32 | ||
| Ulcerative colitis | 33 (50.7%) | 134 (55.3%) | |
| Crohn's disease | 8 (12.3%) | 37 (15.2%) | |
| Indeterminate | 0 (0.0%) | 5 (2.0%) | |
| None | 24 (36.9%) | 66 (27.2%) | |
|
Cholangiocarcinoma found at or before transplant |
4 (6.1%) | 22 (9.0%) | 0.45 |
| Transplant and Donor Characteristics | |||
| Donor age | 42.5 (19.7) | 38.0 (10.2) | 0.12 |
| Female donor | 26 (40.0%) | 113 (46.6%) | 0.34 |
| Donor race | <0.001 | ||
| Asian | 1 (1.5%) | 4 (1.6%) | |
| Black | 4 (6.1%) | 9 (3.7%) | |
| White | 43 (66.1%) | 214 (88.4%) | |
| Unknown | 17 (26.1%) | 15 (6.1%) | |
| Donor ethnicity | <0.001 | ||
| Hispanic/Latino | 3 (4.6%) | 5 (2.0%) | |
| Non-Hispanic/non-Latino | 19 (29.2%) | 215 (88.8%) | |
| Unknown | 43 (66.1%) | 22 (9.0%) | |
| LDLT graft type | |||
| Right lobe | N/A | 227 (93.8%) | |
| Left lobe | 12 (4.9%) | ||
| Left lateral segment | 2 (0.8%) | ||
| Unknown | 1 (0.4%) | ||
| DDLT donor type | |||
| Missing | 3 (4.6%) | N/A | |
| DBD | 60 (92.3%) | ||
| DCD | 2 (3.0%) | ||
| Donor relationship to recipient | |||
| First-degree LDLT | N/A | 120 (49.5%) | |
| Other blood relative LDLT | 23 (9.5%) | ||
| Other LDLT | 99 (40.9%) | ||
| Cold ischemia time (minutes) | 489.3 (170.9) | 80.8 (81.2) | <0.001 |
| Warm ischemia time (minutes) | 45.8 (32.8) | 36.2 (13.6) | 0.03 |
| Type of biliary anastomosis | 0.001 | ||
| All duct-to-duct | 16 (24.6%) | 23 (9.5%) | |
| At least one Roux-en-Y | 49 (75.3%) | 219 (90.4%) | |
Abbreviations: DBD, donation after brain death; DCD, donation after cardiac death; DDLT, deceased donor liver transplant; LDLT, living donor liver transplant; MELD, model for end-stage liver disease; PSC, primary sclerosing cholangitis.