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. Author manuscript; available in PMC: 2017 Aug 1.
Published in final edited form as: Free Radic Biol Med. 2016 Jul 19;97:513–519. doi: 10.1016/j.freeradbiomed.2016.07.016

Table 2.

Mitochondria Stress Test Results from Established Cell Lines

Cell Line Median Age
(passage)
Baseline OCR ± SD
(fmol/min/cell)
Maximal OCR ± SD
(fmol/min/cell)
O2-dependent ATP Production
(%)
Proton Leak
(%)
Spare Resp. Capacity
(fmol/min/cell)
Baseline ECAR ± SD
(μpH/min/cell)
NN1003A 10 7.64 ± 0.37 21.60 ± 0.42 26% 74% 13.93 2.19 ± 0.49
MDCK 8 6.56 ± 0.19**** 11.04 ± 0.60**** 61% 39% 4.48 0.78 ± 0.28**
TM-5 7 2.54 ± 0.09**** 4.57 ± 0.37**** 67% 33% 2.03 0.61 ± 0.13**
CCEE 4 3.77 ± 0.09**** 4.17 ± 0.22**** 60% 40% 0.40 0.56 ± 0.14**

OCR = Oxygen Consumption Rate, ECAR = Extracellular Acidification Rate, Resp. = respiratory

**

In relation to NN1003A, p<0.001

****

In relation to NN1003A, p<0.0001