Table 2.
Cell Line | Median Age (passage) |
Baseline OCR ± SD (fmol/min/cell) |
Maximal OCR ± SD (fmol/min/cell) |
O2-dependent ATP Production (%) |
Proton Leak (%) |
Spare Resp. Capacity (fmol/min/cell) |
Baseline ECAR ± SD (μpH/min/cell) |
---|---|---|---|---|---|---|---|
NN1003A | 10 | 7.64 ± 0.37 | 21.60 ± 0.42 | 26% | 74% | 13.93 | 2.19 ± 0.49 |
MDCK | 8 | 6.56 ± 0.19**** | 11.04 ± 0.60**** | 61% | 39% | 4.48 | 0.78 ± 0.28** |
TM-5 | 7 | 2.54 ± 0.09**** | 4.57 ± 0.37**** | 67% | 33% | 2.03 | 0.61 ± 0.13** |
CCEE | 4 | 3.77 ± 0.09**** | 4.17 ± 0.22**** | 60% | 40% | 0.40 | 0.56 ± 0.14** |
OCR = Oxygen Consumption Rate, ECAR = Extracellular Acidification Rate, Resp. = respiratory
In relation to NN1003A, p<0.001
In relation to NN1003A, p<0.0001