Table 1.

Number of simulations used when presenting results for different models out of a maximum of 1000 simulations

Scenario	EPV	Full	BE 0.05	BE 0.5	Lasso	Ridge	Elastic
1	2.5	928	345	785	681	903	913
1	5	997	649	945	871	976	983
1	10	1000	938	997	979	1000	1000
2	2.5	988	383	897	747	957	977
2	5	1000	784	992	938	994	997
2	10	1000	991	1000	998	1000	1000

Note: Presented in the table are the numbers of simulations where the model computed did not produce constant predictions nor predicted survival probabilities equal to 1. Scenario 1 candidate predictors include clinical variables and biomarkers. Scenario 2 candidate predictors include clinical variables, biomarkers, and genetic variants. BE, backward elimination; EPV, events per variable.