Table 2.

Summary of functional traits of “Entotheonella”.

Functional traits	Interpretation
Calvin–Benson cycle	CO2 fixation
Utilization of various carbon sources	Adaptation to the diverse organic matter in sponge mesohyl
Anaerobic respiration	Energy supply in anoxic environment
Denitrification	Energy supply in anoxic environment
Sulfate reduction	Energy supply in anoxic environment
Peptidase	Compensation for the reduced amino acid synthesis capacity
Endospore formation	Resistance to environmental threats; widespread distribution
Metal resistance	Resistance to environmental threats
Antibiotic resistance	Competition in symbiotic communities; resistance to environmental threats
Eukaryotic-like proteins	Host–microbe recognition
Type II secretion system	Interaction with host environment
Widespread Colonization Island	Tight adhesion
Type VI secretion system	Host–microbe interaction, microbe–microbe competition