Table 1.

Clinical characteristics of patients with mesonephric adenocarcinoma of the vagina reported in the literature. (Modified from Bifulco et al. [2])

	Index case	Bifulco et al. [2]	Hinchey et al. [16]	Bague et al. [3]	Ersahin et al. [1]	Roma AA [6]	Amal et al. [17]
Age (years)	54	58	29	54	55	58	50
Previous surgery	No	TAH + BSO	No	No	VH	SCH	n.k.
Symptoms	Vaginal bleeding	Pelvic pain, pruritus vulvae	Pelvic fullness	“Leiomyomas”	Asymptomatic	Vaginal bleeding	Vaginalbleeding
Size (cm)	2.5 × 1.8	14 × 7 × 6	6 × 6 × 4	4	0.9 × 0.6 × 0.5	5 × 2.5 × 2.5	n.k.
Surgical treatment	ResTu	ResTu + Pelvic + paraaortic LFN	ResTu + BSO	TAH + BSO + colpectomy	Radical upper vaginectomy BSO + pelvic LFN + sampling periaortic LFN	Pelvic exenteration  + ileal conduit	Surgery(unspecified)
Adjuvant treatment	BT + Cis	No	Radiotherapy	No	BT + cisplatin	No	Yes (unspecified)
Follow-up	NED 4.5 years	NED 12 months	NED 4 months	AWD 8.7 years	NED 36 months	1 month	n.k.

ResTu resection of the tumor, AWD alive with disease, BSO bilateral salpingo-oophorectomy, LFN lymphadenectomy, NED no evidence of disease, TAH total abdominal hysterectomy, BT brachytherapy, VH vaginal hysterectomy, SCH supracervial hysterectomy, n.k. not known