Table 4.
Associations with the number of deaths
| Variable | Test | p value (adjusted)a | Effect measure: estimate (95 % CI) |
|---|---|---|---|
| Hypoxia: yes/no | E. Pearson’s Chi-squared test | 1.00 | Odds ratiob: 0.56 (0.15–2.08) |
| Responder: yes/no | E. Pearson’s Chi-squared test | 1.00 | Odds ratio: 2.15 (0.58–8.00) |
| Median infusion rate ≥2 mg/kg/h: yes/no | E. Pearson’s Chi-squared test | 1.00 | Odds ratio: 0.73 (0.21–2.56) |
| Loading dose administered: yes/no | E. Pearson’s Chi-squared test | 1.00 | Odds ratio: 0.16 (0.02–1.45) |
| Number of previously failed AEDs | Brunner-Munzel test | 1.00 | Relative effectc: 0.44 (0.26–0.61) |
| Duration of (S)-KET administration | Brunner-Munzel test | 1.00 | Relative effect: 0.49 (0.31–0.68) |
| Latency from SE to (S)-KET | Brunner-Munzel test | 1.00 | Relative effect: 0.54 (0.36–0.72) |
| Age | Brunner-Munzel test | 0.0014 | Relative effect: 0.80 (0.66–0.94) |
AED antiepileptic drug, CI confidence interval, SE status epilepticus, (S)-KET (S)-ketamine
aThe reported p values have been adjusted for multiple comparisons using the Bonferroni-Holm correction
bThe reported odds ratio represents the quotient of the odds for dying given hypoxia = yes and the odds for dying given hypoxia = no. Analogous interpretations hold for the other odds ratios reported in the table
cThis quantity can be interpreted as an estimate of the probability that the value of the variable is lower for the alive than for the deceased