Table 2.

Comparison between the incidences of extrapyramidal symptoms in the placebo-controlled trails: odds ratios

	Model	Studies (n)	Point estimate (95 % CI)	Z	p value	Q-statistic	p value Q-statistic
EPS	Fixed	5	3.85 (2.37–6.28)	5.42	0.00	4.04	0.40
	Random	5	3.85 (2.36–6.30)	5.37	0.00
Dystonia	Fixed	5	1.35 (0.52–3.48)	0.61	0.54	3.80	0.43
	Random	5	1.35 (0.52–3.48)	0.61	0.54
Akathisia	Fixed	8	1.38 (0.77–2.47)	1.07	0.29	13.05	0.07
	Random	8	1.29 (0.54–3.12)	0.57	0.57
Parkinsonism	Fixed	3	4.91 (2.76–8.75)	5.40	0.00	0.58	0.75
	Random	3	4.91 (2.76–8.75)	5.40	0.00
Tremor	Fixed	4	3.46 (1.42–8.43)	2.73	0.01	1.97	0.58
	Random	4	3.46 (1.42–8.43)	2.73	0.01
Tardive dyskinesia	Fixed	5	1.92 (0.43–8.59)	0.85	0.39	0.37	0.99
	Random	5	1.92 (0.43–8.59)	0.85	0.39

CI confidence interval, EPS extrapyramidal symptoms