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Selectivity of AmdA, AmdV, and AmdP on derivatives of 2-arylpropionic acids. Selected GC-chromatograms of (R)-flurbiprofen (left) and (R)-naproxen (right) after AMDase-catalyzed decarboxylation (here using AmdA) of the corresponding aryl malonic acids. Racemic arylpropionates are showαn in gray. The measurement was done using a FS-Hydrodex-β-6-TBDM column from Macherey-Nagel with an isothermic temperature of 160°C for naproxen and 170°C for flurbiprofen.
