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. 2016 Aug 25;10:396. doi: 10.3389/fnins.2016.00396

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Copyright © 2016 Provenzano, Corradi, Monsorno, Fedrizzi, Ricceri, Scattoni and Bozzi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Differentially expressed genes in the BTBR hippocampus. (A) Schematic representation of BTBR hippocampal DEGs, as compared to control B6 mice. A total of 1016 DEGs were identified, (580 down-regulated, 436 up-regulated). (B) qRT-PCR validation of differentially expressed genes. qRT-PCR results for all the evaluated genes were in agreement with microarray results. Values are expressed as each gene/L41 comparative quantitation ratios normalized on the expression of WT (mean ± s.e.m of three replicates from pools of six animals per genotype; p < 0.05, Student's t-test, BTBR vs. B6).