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SiO2NPs promote lysosomal degradation of Dvl. (A) The effect of SiO2NPs on protein levels of Dvl in the absence or presence of Wnt3a in 293T cells. (B) The effect of 100 μg/mL SiO2NPs on protein levels of Dvl in 3T3-L1 and MDA-MB-231 cells. (C) The effect of 100 μg/mL SiO2NPs on protein levels of Lrp6, GSK3β, Akt and p62 in 293T cells. (D) The effect of 100 μg/mL SiO2NPs on protein levels of Dvl in the absence or presence of 3-MA or LY294002 in 293T cells.
