Skip to main content
. 2016 Aug 8;6(11):1934–1946. doi: 10.7150/thno.16023

Figure 3.

Figure 3

Over-expression of GPx3 significantly suppressed migration, invasiveness and metastasis of HCC cells. (A) Over-expression of GPx3 significantly suppressed migration of HCC cells in wound healing assay. (B) Over-expression of GPx3 significantly suppressed invasiveness of HCC cells in Matrigel invasion assay, *P < 0.01. The error bar represented as mean ± SD. (C) Over-expression of GPx3 significantly inhibited intra-hepatic tumor spread in orthotopic nude mice liver cancer model (n = 6). (D) Over-expression of GPx3 significantly inhibited lung metastasis of HCC cells injected through tail vein of nude mice (n = 3).