Table 5. Aqueous humor levels of 27 types of cytokines in subgroup A and subgroup B and changes after IVR.

	Subgroup A (n = 15)	Subgroup B (n = 24)	Preinjection (n = 11)	Postinjection (n = 11)	P Value
							Subgroup A vs Subgroup B	Preinjection vs Postinjection
IL-2	1.3 (0–3.3)	1.8 (0–11.2)	2.0 (0–11.2)	1.8 (0–2.8)	0.187	0.028
IL-10	4.1 (2.8–6.1)	5.0 (2.2–15.2)	5.3 (2.2–15.2)	2.4 (0–4.3)	0.043	0.004
IL-15	6.6 (3.5–10.5)	7.9 (0–27.8)	8.1 (3.8–18.1)	7.8 (3.1–10.3)	0.112	0.175
IL-17	9.5 (0–15.1)	9.8 (0–55.7)	9.5 (0–55.7)	9.2 (0–11.2)	0.675	0.221
basic FGF	13.4 (7.5–28.3)	12.9 (5.0–88.4)	12.5 (5.0–88.4)	10. 0 (0–42.4)	0.544	0.041
GM-CSF	169.0 (114.2–291.8)	171.8 (35.6–1450.1)	207.6 (71.5–1450.1)	165.4 (39.6–259.9)	0.624	0.075
IL-1b	0 (0–3.2)	0	0	0	0.206	—
IL-1ra	0 (0–12.0)	5.0 (0–131.3)	0 (0–131.3)	0 (0–29.4)	0.122	0.612
IL-4	0	0	0	0 (0–0.3)	—	0.317
IL-5	0	0	0	0	—	—
IL-6	3.4 (0–7.5)	3.0 (0–120.9)	2.7 (0–120.9)	4.5 (1.9–698.2)	0.897	0.016
IL-7	1.6 (0–3.2)	2.0 (0–3.6)	2.1 (0–3.6)	1.5 (0–3.4)	0.056	0.663
IL-8	0	0 (0–4.5)	0 (0–4.1)	0 (0–16.5)	0.100	0.317
IL-9	0 (0–2.0)	0 (0–5.2)	0 (0–1.4)	0 (0–1.4)	1.000	1.000
IL-12	10.0 (4.2–15.3)	11.5 (0–25.0)	10.3 (0–25.0)	0 (0–9.1)	0.238	0.008
IL-13	1.8 (0.6–6.5)	2.0 (0–5.4)	2.1 (0–5.4)	1.7 (0.5–3.4)	0.462	0.386
Eotaxin	0	0	0	0	—	—
G-CSF	0	0	0	0 (0–12.8)	—	0.317
IFN-γ	0	0 (0–9.6)	0	0 (0–9.3)	0.429	0.317
IP-10	59.4 (0–202.7)	39.4 (0–407.4)	32.2 (0–407.4)	46.2 (1.6–1375.8)	0.231	0.110
MCP-1	331.5 (180.7–443.7)	346.4 (185.5–596.7)	343.2 (206.1–476.8)	311.2 (171.6–625.9)	0.335	0.648
MIP-1a	0.7 (0–1.1)	0 (0.3–3.9)	0 (0–3.9)	0.7 (0–0.8)	0.616	0.674
MIP-1b	5.1 (1.9–13.3)	7.9 (3.2–22.0)	7.1 (3.2–13.5)	7.0 (4.0–15.4)	0.030	0.407
PDGF-bb	0	0	0	0	—	—
RANTES	0	0	0	0	—	—
TNF-α	0	0	0	0 (0–5.4)	—	0.317
VEGF	37.5(18.5–69.1)	44.8(17.6–108.8)	40.3 (17.6–108.8)	5.7 (0–59.9)	0.097	0.003

Values in boldface type indicate statistical significance. Levels are expressed as the median (range) pg/ml.