TABLE 3.
Serum 25(OH)D concentrations in relation to fertilization rate1
| 2PN2/MII3 | All cycles4 (n = 141) | 2PN2/MII3 | IVF cycles4 (n = 71) | 2PN2/MII3 | ICSI cycles4 (n = 70) | |
| Serum 25(OH)D,5 nmol/L | ||||||
| Q1 [65.0 (33.5–75.0)] | 251/386 | 0.62 (0.51, 0.72) | 158/235 | 0.63 (0.47, 0.77) | 93/151 | 0.52 (0.36, 0.68) |
| Q2 [83.1 (75.9–86.2)] | 196/349 | 0.53 (0.43, 0.63) | 119/196 | 0.53 (0.39, 0.67) | 77/153 | 0.38 (0.24, 0.55) |
| Q3 [92.4 (86.8–104.6)] | 228/327 | 0.67 (0.56, 0.76) | 52/95 | 0.50 (0.31, 0.68) | 176/232 | 0.73 (0.59, 0.83) |
| Q4 [115.0 (107.8–155.5)] | 264/356 | 0.73 (0.63, 0.80) | 137/185 | 0.71 (0.55, 0.83) | 127/171 | 0.74 (0.62, 0.83) |
| P6 | 0.03 | 0.39 | 0.004 | |||
| P-heterogeneity | 0.05 | |||||
1
n = 100 women, 141 cycles with attempted fertilization. ICSI, intracytoplasmic sperm injection; IVF, in vitro fertilization; MII, metaphase II; Q, quartile; 2PN, 2 pronuclei; 25(OH)D, 25-hydroxyvitamin D.
2
Number of oocytes with 2PN after insemination.
3
Number of oocytes in MII.
4
Values are marginal means (95% CIs) adjusted for age, BMI, infertility diagnosis, race, dietary patterns, folate, and vitamin B-12 serum concentrations.
5
Values are medians (ranges).
6
The median concentration of vitamin D in each group was used as a continuous variable in the model.