Table 3. Sensitivity analyses of efficacy of immunotherapy in patients with advanced NSCLC.
Type of immunotherapy* | Interventions | Number of trials | Pooled HR (95%CI) |
---|---|---|---|
Therapeutic vaccines | I vs. P | 4 | 0.82 (0.70–0.94) |
Immune checkpoint inhibitors | I vs. C | 2 | 0.67 (0.53–0.80) |
Other immunomodulators | I + C vs. C + (P) | 2 | 1.01 (0.97–1.05) |
I vs. P | 2 | 0.88 (0.52–1.24) |
*Studies that Jadad score less than 3 were excluded. I: immunotherapy; P: placebo; C: chemotherapy.