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. 2016 Aug 25;6:32027. doi: 10.1038/srep32027

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Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Panel A displays the summary of top 10 canonical pathways positively (left panel) and negatively (right panel) correlated to nCMPK1 expression (CHON_DERM_METABOLISM: chondroitin sulfate dermatan sulfate metabolism, NES: normalized enrichment score). Panel B displays examples of the pathways associated with nCMPK1 expression. Left panel: enrichment plots of the most significant pathways; Middle panel: heatmaps of the significant genes in ‘core matrisome’ and ‘DNA replication’ pathways; Right panel: expression of the heatmap genes in 4 groups based on nCMPK1 expression.