Table 2. Summary of the differential abundance analysis for pancreatic miRNAs in circulation.

	logFC	FC	P.Value	adj.P.Val		logFC	FC	P.Value	adj.P.Val
PreT2D-Healthy					LADA-Healthy
miR-126	−0.95	0.52	0.0243	0.1217	miR-126	−0.03	0.98	0.9512	0.9868
miR-146a	−0.94	0.52	0.0207	0.1217	miR-146a	0.27	1.21	0.6127	0.9868
miR-148a	−0.96	0.51	0.0608	0.1521	miR-148a	0.01	1.01	0.9868	0.9868
miR-21	−0.43	0.74	0.2240	0.3734	miR-21	0.08	1.05	0.8715	0.9868
miR-24	−0.73	0.60	0.0823	0.1647	miR-24	0.43	1.35	0.4336	0.9868
miR-29a	−1.08	0.47	0.0530	0.1521	miR-29a	−0.64	0.64	0.3861	0.9868
miR-30d	−0.12	0.92	0.8110	0.8110	miR-30d	−0.27	0.83	0.6800	0.9868
miR-34a	−0.22	0.86	0.7658	0.8110	miR-34a	1.37	2.59	0.1717	0.9868
miR-375	−0.62	0.65	0.4004	0.5005	miR-375	−0.26	0.84	0.7910	0.9868
miR-376a	−0.62	0.65	0.2767	0.3953	miR-376a	0.16	1.12	0.8324	0.9868
T2D-Healthy					T1D-Healthy
miR-126	0.79	1.73	0.0506	0.0894	miR-126	0.48	1.39	0.1794	0.2243
miR-146a	0.34	1.26	0.3828	0.3828	miR-146a	0.53	1.44	0.1243	0.1776
miR-148a	0.97	1.96	0.0481	0.0894	miR-148a	1.11	2.15	0.0119	0.0396
miR-21	0.74	1.67	0.0301	0.0894	miR-21	0.86	1.81	0.0052	0.0396
miR-24	0.59	1.50	0.1428	0.2040	miR-24	0.85	1.81	0.0181	0.0452
miR-29a	1.03	2.04	0.0537	0.0894	miR-29a	0.80	1.74	0.0920	0.1582
miR-30d	1.41	2.66	0.0034	0.0338	miR-30d	0.70	1.63	0.0949	0.1582
miR-34a	1.72	3.30	0.0184	0.0894	miR-34a	0.70	1.63	0.2723	0.3026
miR-375	0.82	1.77	0.2460	0.3023	miR-375	1.68	3.21	0.0085	0.0396
miR-376a	−0.60	0.66	0.2721	0.3023	miR-376a	0.36	1.28	0.4602	0.4602

The differential abundance analysis was implemented in the R environment using the limma package. Features (miRNAs) are sorted alphabetically. Significant values [p < 0.05 and/or adjusted p value (FDR) < 0.13] are highlighted in bold and underlined.