Figure 7. Network of factors demonstrating shared impact on gut microbial composition, among neonates.

The network includes factors associated with compositional differences in the neonatal gut microbiome in either single or multi-factor models. Compositional similarity for each pair of factors was defined as the percentage of overlapping significant taxa among all significant taxa between the two factors; two factors were connected in the network if they had at least a 15% overlap in shared associated taxa (≥80^th percentile of percentages). In order to disentangle similarity based on compositional impact and similarity due to high correlation, between-factor connections are colored orange if they are significantly correlated (grey otherwise). Abbreviations: BMI, body mass index; ETS, environmental tobacco smoke; NSV, neonatal study visit at 1-month of age.