Table 2.

The frequency of methylenetetrahydrofolate reductase gene (MTHFR) C677T polymorphism allele/genotype prevalence.

Author (Ref)	Prevalence of MTHFR C677T Genotype						Prevalence of Allele Frequency
	CC		CT		TT		C		T
	Case	Control	Case	Control	Case	Control	Case	Control	Case	Control
Neugebauer, S. et al. [12]	26	20	38	13	12	3	90	53	62	19
Fujita, H. et al. [13]	31	20	57	39	17	9	119	79	91	57
Lauszus, F.F. et al. [14]	47	542	57	455	8	87	151	1539	73	629
Wang, L.Q. et al. [15]	8	94	27	86	27	22	43	274	81	130
Yang, G.Q. et al. [16]	8	75	33	111	19	45	49	261	71	201
Maeda, M. et al. [17]	18	37	20	58	13	10	56	132	46	78
Santos, K.G. et al. [18]	34	41	53	53	12	17	121	135	77	87
Sun, J. et al. [19]	33	82	46	45	31	28	112	209	108	101
Yoshioka, K. et al. [20]	33	100	50	132	15	36	116	332	80	204
Huang, D.F. et al. [21]	17	26	25	18	8	3	59	70	41	24
Yi, X.X. et al. [22]	68	35	110	19	71	11	246	89	252	41
Errera, F.I. et al. [23]	61	36	66	57	14	14	188	129	94	85
Liu, D.M. et al. [24]	18	47	16	25	10	12	52	119	36	49
Maeda, M. et al. [25]	31	43	28	62	16	10	90	148	60	82
Ukinc, K. et al. [26]	14	14	11	13	0	0	39	41	11	13
Ren, M. et al. [27]	26	77	78	95	57	41	130	249	192	177
Yigit, S. et al. [28]	38	85	30	55	13	9	106	225	56	73
Simoes, M.J. et al. [29]	69	45	60	30	19	4	198	120	98	38
Total	580	1419	805	1366	362	361	1965	4204	1529	2088