Table 2. Associations between risk of vulval cancer, age at menopause, and use of menopausal hormone therapy in postmenopausal women.

Exposure	Cases/population at risk	Relative riska	95% Confidence interval	P-value
Age at menopause in women with natural menopause or oophorectomy who have never used hormone therapy
50+ Years	158/237 144	1.00		<0.001
<50 Years	167/175 489	1.52	(1.22–1.89)
Use of menopausal hormone therapy at baseline, all postmenopausal women
Never	401/493 167	1.00		0.54
Past	142/192 727	0.94	(0.77–1.14)
Current	252/424 544	0.86	(0.73–1.02)

^aRelative risks adjusted, where possible, for smoking, alcohol use, body mass index, age at menarche, oral contraceptive use, parity, tubal ligation, cervical intraepithelial neoplasia grade 3, diabetes, hysterectomy/oophorectomy, and deprivation.