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. 2016 Aug 25;6:32288. doi: 10.1038/srep32288

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Copyright © 2016, The Author(s)

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(1) CHIKV infection of monocytes triggers (2) the production of IFNβ. (3) Other leukocytes are stimulated by IFNβ and produce (4) one or a combination of soluble factors that stimulates MCP-1 expression in monocytes.