Table 1.
Expression of heterogeneous nuclear ribonucleoprotein H1protein and its clinical significance in 125 esophageal squamous cell carcinomaspecimens n (%)
| Characteristics | All cases (n) |
HNRNPH1 |
P value1 | ||
| Negative | Weak | Strong | |||
| Tissues | |||||
| Normal | 125 | 53 (42.4) | 44 (35.2) | 28 (22.4) | 0.0005 |
| Cancer | 125 | 49 (39.2) | 22 (17.6) | 54 (43.2) | |
| Age (yr) | 0.5422 | ||||
| ≥ 60 | 71 | 26 (36.6) | 16 (22.5) | 29 (40.8) | |
| < 60 | 54 | 23 (42.6) | 6 (11.1) | 25 (46.3) | |
| Gender | 0.9615 | ||||
| Male | 90 | 34 (37.8) | 17 (18.9) | 39 (43.3) | |
| Female | 35 | 15 (42.9) | 5 (14.2) | 15 (42.9) | |
| Tumor differentiation | 0.0652 | ||||
| Well | 29 | 15 (51.7) | 5 (17.2) | 9 (31.1) | |
| Moderately | 72 | 26 (36.1) | 16 (22.2) | 30 (41.7) | |
| Poorly | 24 | 8 (33.3) | 1 (4.2) | 15 (62.5) | |
| Tumor differentiation | 0.0337 | ||||
| Well + moderately | 101 | 41 (40.6) | 21 (20.8) | 39 (38.6) | |
| Poorly | 24 | 8 (33.3) | 1 (4.2) | 15 (62.5) | |
| Lymph Node Metastasis2 | 0.1839 | ||||
| Present | 42 | 14 (33.3) | 9 (21.4) | 19 (45.2) | |
| Not present | 36 | 18 (50.0) | 7 (19.4) | 11 (30.6) | |
1
The strong expression of HNRNPH1 was compared with negative and weak expression;
2
Only 78 cases had information on lymph node metastasis. HNRNPH1: Heterogeneous nuclear ribonucleoprotein H1; ESCC: Esophageal squamous cell carcinoma.