Table 2.
Correlation between Tiam1 expression and the clinicopathological features of breast cancer
| Variables | No. of cases | Tiam1 strongly positive cases (%) | χ 2 | P value |
|---|---|---|---|---|
| Age | 0.186 | 0.666 | ||
| ≥ 50 | 84 | 37 (44.0 %) | ||
| < 50 | 69 | 28 (40.6 %) | ||
| Menopausal status | 1.981 | 0.159 | ||
| Premenopausal | 63 | 31 (49.2 %) | ||
| Postmenopausal | 90 | 34 (37.8 %) | ||
| Molecular type | 5.142 | 0.162 | ||
| Luminal A | 39 | 21 (53.8 %) | ||
| Luminal B | 46 | 21 (45.7 %) | ||
| TNBC | 39 | 15 (35.9 %) | ||
| Her2+ | 29 | 8 (27.6 %) | ||
| Tumor stage | 10.136 | 0.002** | ||
| T0-T1 | 84 | 26 (31.0 %) | ||
| T2-T3 | 69 | 39 (56.5 %) | ||
| LN metastasis | 0.364 | 0.546 | ||
| Absent | 57 | 26 (45.6 %) | ||
| Presence | 96 | 39 (40.6 %) | ||
| ER | 0.453 | 0.501 | ||
| Positive | 87 | 39 (44.8 %) | ||
| Negative | 66 | 26 (39.4 %) | ||
| PR | 0.489 | 0.484 | ||
| Positive | 78 | 31 (39.7 %) | ||
| Negative | 75 | 34 (45.3 %) | ||
| Her2 | 4.003 | 0.046* | ||
| Positive | 41 | 12 (29.3 %) | ||
| Negative | 112 | 53 (47.3 %) | ||
| Ki-67 | 7.075 | 0.008** | ||
| Positive | 102 | 51 (50.0 %) | ||
| Negative | 51 | 14 (27.5 %) |
* p < 0.05, ** p < 0.01