Table 3.

Univariate and Multivariate survival analyses (Cox regression model) of various factors in 153 patients with breast cancer

Factors	DFS Hazard ratio (95 % CI)	P value	OS Hazard ratio (95 % CI)	P value
Univariate analyses
Age	1.172(0.851–1.616)	0.331	1.162(0.844–1.601)	0.358
Menopausal status	1.015(0.831–1.239)	0.885	1.016(0.831–1.242)	0.878
Molecular type	1.373(0.995–1.896)	0.054	1.385(1.004–1.912)	0.047*
Tumor stage	0.685(0.590–0.796)	0.000**	0.694(0.599–0.805)	0.000**
LN metastasis	1.287(0.927–1.786)	0.131	1.335(0.961–1.855)	0.085
ER	1.171(0.848–1.616)	0.338	1.163(0.843–1.605)	0.359
PR	1.016(0.736–1.404)	0.922	1.048(0.760–1.446)	0.774
Her2	1.646(1.186–2.285)	0.003**	1.740(1.245–2.431)	0.001**
Ki-67	1.058(0.765–1.4622)	0.734	1.075(0.777–1.485)	0.663
Tiam1	1.781(1.276–2.487)	0.001**	1.671(1.204–2.320)	0.002**
Multivariate analyses
Tiam1	1.470(1.056–2.047)	0.022*	1.549(1.112–2.157)	0.010*
Molecular type			1.340(0.963–1.865)	0.082
Tumor stage	0.567(0.413–0.778)	0.000**	0.585(0.425–0.805)	0.001**
Her2	0.585(0.290–1.179)	0.134	0.617(0.298–1.276)	0.617

95 % CI 95 % confidence interval

* p < 0.05, ** p < 0.01