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. 2016 Aug 25;8(1):91. doi: 10.1186/s13073-016-0341-9

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Candidate de novo mutated genes identified by VARPRISM, Poisson tests, and fitDNM. Left, the pie chart shows the relative proportion of genes found by VARPRISM and any other tests (Poisson-all, Poisson-LGD, or fitDNM). Right, the pie chart further illustrates the level of evidence for genes found by VARPRISM only. Gene names in each category were listed below