Table 3.
Comparison of the invasion depth diagnosis between endoscopic ultrasonography and conventional endoscopy
| Clinical diagnosis |
Histologic diagnosis |
EUS
diagnosis |
P2 |
Histologic
diagnosis |
Accuracy | P (vs EUS) | ||||
| M/SM1 | SM2 | Overall accuracy | Accuracy1 | M/SM1 | SM2 | |||||
| Diagnosis | M/SM1 | 81 | 9 | 71.2 | 82.6 | 97 | 18 | 79.7 | 0.54 | |
| SM2 | 14 | 28 | 13 | 25 | ||||||
| Macroscopic type | 0.30 | |||||||||
| I | M/SM1 | - | - | - | - | 5 | 1 | 88.9 | - | |
| SM2 | - | - | 0 | 3 | ||||||
| IIa/IIb | M/SM1 | 26 | 4 | 67.3 | 77.8 | 32 | 5 | 78.8 | 0.90 | |
| SM2 | 6 | 9 | 6 | 9 | ||||||
| IIc | M/SM1 | 55 | 5 | 80.4 | 85.1 | 60 | 12 | 79.3 | 0.32 | |
| SM2 | 8 | 19 | 7 | 13 | ||||||
| Location | 0.55 | |||||||||
| Upper | M/SM1 | 21 | 2 | 74.4 | 80 | 24 | 4 | 80.0 | > 0.99 | |
| SM2 | 6 | 11 | 5 | 12 | ||||||
| Middle | M/SM1 | 40 | 7 | 69.9 | 78.5 | 44 | 11 | 78.3 | 0.98 | |
| SM2 | 7 | 11 | 4 | 10 | ||||||
| Lower | M/SM1 | 19 | 2 | 62.2 | 85.2 | 29 | 3 | 82.1 | > 0.99 | |
| SM2 | 2 | 4 | 4 | 3 | ||||||
| Histology | 0.79 | |||||||||
| Diff. | M/SM1 | 71 | 10 | 70.4 | 83 | 77 | 12 | 80.5 | 0.63 | |
| SM2 | 8 | 17 | 11 | 18 | ||||||
| Undiff. | M/SM1 | 9 | 1 | 75.0 | 84 | 20 | 6 | 77.1 | > 0.99 | |
| SM2 | 4 | 12 | 2 | 7 | ||||||
| Ulcer scar | < 0.0001 | |||||||||
| Positive | M/SM1 | 3 | 2 | 46.7 | 50 | 7 | 4 | 58.6 | 0.51 | |
| SM2 | 12 | 11 | 8 | 10 | ||||||
| Negative | M/SM1 | 77 | 7 | 75.6 | 89.4 | 90 | 14 | 84.7 | 0.29 | |
| SM2 | 4 | 16 | 5 | 15 | ||||||
| Indication for ER | < 0.0001 | |||||||||
| Absolute | M/SM1 | 37 | - | 80.4 | 97.4b | 43 | - | 84.3f | 0.07 | |
| SM2 | 1 | - | 8 | - | ||||||
| Expanded | M/SM1 | 28 | - | 75.7 | 87.5d | 33 | - | 86.8h | > 0.99 | |
| SM2 | 4 | - | 5 | - | ||||||
| Non-indication | M/SM1 | 12 | 13 | 56.1 | 62.7bd | 16 | 18 | 64.1fh | > 0.99 | |
| SM2 | 9 | 25 | 5 | 25 | ||||||
Accuracy1 was calculated with the exception of 21 inconclusive cases of EUS; P2 indicates a significant difference in Accuracy1.
b
P < 0.0001;
d
P = 0.02;
f
P = 0.02;
h
P = 0.01. EUS: Endoscopic ultrasonography; CE: conventional endoscopy; Diff: Differentiated-type; Undiff: Undifferentiated-type; ER: Endoscopic resection.