TABLE 2.
Region | No. of isolates with mutation | No. (%) correlated with: |
Pa | |
---|---|---|---|---|
Low-level PZA resistance (MIC ≤ 500 mg/liter) | High-level PZA resistance (MIC > 500 mg/liter) | |||
Codons 51–76 | 34 | 5 (14.7) | 29 (85.3) | |
Codons 130–142 | 28 | 0 (0.0) | 28 (100.0) | |
Codons 163–180 | 14 | 0 (0.0) | 14 (100.0) | <0.001 |
Codons 94–97 | 16 | 6 (37.5) | 10 (62.5) | |
Nucleotide −11 to codon 16 | 29 | 21 (72.4) | 8 (27.6) |
Calculated by comparing all the codon regions of the pncA gene by using the Fisher exact test.