TABLE 2.

Antibacterial peptide dosages^a

Compound	Target 1× MIC (μg μl−1) in fly		amt injected for 1× MIC (μg)		amt of compound injected (mg kg fly−1)
	8325-4	USA300	8325-4	USA300	8325-4	USA300
Peptides
Nisin	0.01	0.004	0.005	0.002	6.25	2.5
NAI-107	0.00006	0.00025	0.00003	0.000125	0.04	0.16
GN-2	0.008		0.004		4
GN-4	0.004		0.002		2.5
HHC-9	0.004		0.002		2.5
HHC-36	0.008		0.004		5
Peptoids
GN-2 Npm9	0.032		0.016		20
GN-2 Ntrp5–8	0.016		0.008		10
GN-4	0.064		0.032		4
Control antibiotics
Ampicillin	0.00001		0.000005		0.01
Vancomycin		0.002		0.001		1.25

^aAll data presented are based on 1× MICs of the compounds. The fly weight was 0.8 mg, and the fluid content of a fly was estimated to be 0.5 μl (see Materials and Methods).