TABLE 1.
Antimicrobial susceptibility testing of each isolate and transconjugant
| Antibiotic agent | MICs (μg/ml) for: |
|||
|---|---|---|---|---|
| A. xylosoxidans KUN4507 | K. pneumoniae KUN4843 | K. pneumoniae KUN5033 | Transconjuganta | |
| Piperacillin | ≤4 | >64 | >64 | >64 |
| Piperacillin-tazobactamb | 4/4 | 4/4 | 8/4 | 8/4 |
| Cefazolin | >8 | >8 | >8 | >8 |
| Cefotaxime | >16 | ≤1 | >16 | >16 |
| Ceftazidime | >16 | ≤1 | >16 | >16 |
| Cefepime | >16 | ≤1 | >16 | >16 |
| Imipenem | >8 | ≤0.25 | >8 | 8 |
| Meropenem | >8 | ≤0.25 | 4 | 2 |
| Aztreonam | >16 | ≤1 | ≤1 | ≤1 |
| Gentamicin | >8 | ≤1 | ≤1 | ≤1 |
| Tobramycin | >8 | ≤1 | ≤1 | ≤1 |
| Amikacin | >32 | ≤1 | ≤1 | ≤1 |
| Ciprofloxacin | >4 | >4 | >4 | >4 |
| Levofloxacin | >4 | >4 | >4 | >4 |
| Minocycline | >16 | >16 | >16 | >16 |
| Colistin | 4 | ≤2 | ≤2 | ≤2 |
a
Transconjugant derived from K. pneumoniae KUN4843 that acquired blaIPM-19.
b
The MIC of piperacillin-tazobactam is indicated by the concentration of piperacillin-tazobactam.