TABLE 2.
Antibacterial activity of compound 19 (azi-OON-Cl) and standard antibiotics against recent RTI-related clinical isolates of S. pneumoniae collected in Croatiaa
| Compound | MIC (μg/ml) |
||
|---|---|---|---|
| 50% | 90% | Range | |
| 19 (azi-OON-Cl) | ≤0.015 | ≤0.015 | ≤0.015–0.125 |
| Telithromycin | ≤0.015 | 0.125 | ≤0.015–0.5 |
| Azithromycin | ≤0.125 | >64 | ≤0.125–>64 |
| Clindamycin | ≤0.125 | >64 | ≤0.125–>64 |
| Tetracycline | ≤0.125 | 32 | ≤0.125–>64 |
| Penicillin G | ≤0.015 | 2 | ≤0.015–8 |
| Cefotaxime | ≤0.015 | 1 | ≤0.015–8 |
| Moxifloxacin | 0.125 | 0.125 | 0.06–0.25 |
a
Data are for 73 S. pneumoniae isolates.