FIG 5.

Drug-modulated ATPase activities of reconstituted enterococcal ABC exporters. The ATPase activities of EfrAB, EfrCD, EfrEF, and EF0942/41 were measured in the presence of daunorubicin (a), ethidium (b), and Hoechst 33342 (c) at drug concentrations ranging from 0.1 μM to 200 μM. ATPase activities were normalized to the basal activity of the respective transporter in the absence of drugs (set at 100%). The error bars correspond to the standard deviations for three technical replicates. The x axis has a logarithmic scale.