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. 2016 Aug 22;60(9):5400–5411. doi: 10.1128/AAC.00661-16

TABLE 2.

Complementation of E. faecalis 4205 ΔefrCD with a plasmid producing wild-type EfrCD or the inactive E512Q mutant from the native promoter

E. faecalis 4205 genotype Complementation MIC (μg/ml)a of:
Daunorubicin Hoechst 33342
ΔefrCD EfrCD 32 2
EfrCD_E512Q 2 0.25
Wild type EfrCD 32 2
EfrCD_E512Q 16 1
a

MICs were determined in cation-supplemented Mueller-Hinton broth with 10 μg/ml erythromycin after 18 h at 37°C from a minimum of three independent experiments.