TABLE 3.

Comparison of regression modeling for outcomes 30 days after diagnosis of Staphylococcus aureus bacteremia, comparing participants with MICs of <2 μg/ml to those with MICs of 2 μg/ml

Model	HR (95% confidence interval)	P value
Mortality, all cause (n = 46)
Cox regression, unadjusted	1.19 (0.59, 2.41)	0.63
Cox regression, adjusteda	1.19 (0.55, 2.59)	0.66
Cox regression with propensity score and covariate adjustmentb	0.86 (0.41, 1.80)	0.70
Readmission, all cause (n = 47)
Cox regression, unadjusted	0.94 (0.45, 1.95)	0.87
Cox regression, adjustedc	1.03 (0.49, 2.16)	0.94
Cox regression with propensity score and covariate adjustmentd	0.97 (0.46, 2.04)	0.94
Recurrence of bacteremia (n = 1)
Cox regression, unadjusted	—g
Cox regression, adjusted	—
Cox regression with propensity score and covariate adjustment	—
Composite (n = 93)
Cox regression, unadjusted	1.05 (0.64, 1.75)	0.84
Cox regression, adjustede	0.98 (0.58, 1.66)	0.95
Cox regression with propensity score and covariate adjustmentf	0.94 (0.55, 1.58)	0.80

^aAdjustment covariates included methicillin resistance, age, race, gender, hospital onset, Charlson comorbidity index, recent long-term-care facility stay, immunosuppressive medication, cefazolin therapy, nafcillin therapy, and advanced beta-lactam use (ceftaroline, cefepime, or carbapenem class).

^bAdjustment covariates included advanced beta-lactam use (ceftaroline, cefepime, or carbapenem class) and propensity score.

^cAdjustment covariates included methicillin resistance, age, race, gender, hospital onset, Charlson comorbidity index, recent long-term-care facility stay, and cefazolin therapy.

^dAdjustment covariates included only the propensity score.

^eAdjustment covariates included methicillin resistance, age, race, gender, hospital onset, Charlson comorbidity index, recent long-term-care facility stay, and advanced beta-lactam use (ceftaroline, cefepime, or carbapenem class).

^fAdjustment covariates included advanced beta-lactam use (ceftaroline, cefepime, or carbapenem class), recent long-term-care facility stay, and propensity score.

^g—, the model was not undertaken given limited events.