FIG 2.

Comparison of virulence of rifaximin-resistant mutants in hamsters. WT, parent strain CD43; Arg₅₀₅Lys, mutant strain CD43-D5; Asp₄₉₂Tyr, mutant strain CD43-D3; Ser₅₅₀Tyr, mutant strain CD43-D9. No significant differences exist between the means as determined by one-way analysis of variance (ANOVA) (P = 0.28). The number of animals in each group was n = 5 for WT, n = 6 for Arg₅₀₅Lys, n = 5 for Asp₄₉₂Tyr, and n = 4 for Ser₅₅₀Tyr. CD43 mutants bearing His₅₀₂Asn and His₅₀₂Tyr strains were unavailable at the time of the experiments.