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. 2016 Jul 8;12(3):1821–1825. doi: 10.3892/ol.2016.4829

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Copyright: © Chen et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — Pharmacological inhibition of taffazin/TEA domain interactions decreases cell viability and migration, and induces EMT in ovarian cancer cells. SKOV-3 cells were treated with the indicated concentrations of verteporfin for 24 h prior to analysis. (A) Cell viability was analyzed by Cell Counting kit-8 assay. (B) Cell migration was analyzed by Transwell assay. Representative images (×100 magnification) of each group are shown. Crystal violet staining. *P<0.05, Student's t-test. (C) Protein expression was analyzed by western blotting. DMSO, dimethyl sulfoxide; VIM, vimentin; ZO-1, zonula occludens-1.