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| Tumor | Drug route/schedule | Max. tolerated total dosea (mg/kg) | %T/Cb | %ILSc |
|---|---|---|---|---|
| Panc03 | s.c., qd 3-9 | 781 | 17 | |
| Colo38 | s.c., qd 3-9 | 504 | 0 | |
| Mam16C | s.c., qd 1-4 | 263 | 15 | |
| B16 | i.p., qd 1,5,9 | 1500 | 66 | |
| P388 | i.p., qd 1,5,9 | 1014 | 90 |
aMaximum non-lethal dose; btumor growth inhibition where T and C are median tumor weights of the treatment and control groups respectively; cpercent increased life span.
