Fig. (6).

The in vivo effects of PD in nude mice bearing PC3 xenograft tumors. PD was injected intraperitoneally (i.p.) at doses of 1 mg/kg/d and 2.5 mg/kg/d, 5 d/wk for 24 days. A. Animals were monitored for changes in body weight every three days as an indicator of toxicity. B. At the end of the experiment, representative tumors were removed and photographed. C. The tumors were measured every three days to assess their growth.