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Deletion of the pezAT operon leads to cells with increased transformability. Competent pneumococcal cells of indicated strains were treated or not with CSP-1 and incubated with transforming DNA prepared from total cell lysates (Chr) or from homogeneous DNA amplified by PCR from total cell lysates (Str41). t-test was used to evaluate the statistical differences and the asterisk symbol (∗) indicates statistical significance (p-value < 0.05) between R6wt and R6ΔPezAT.
