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. 2016 Aug 19;11:4051–4063. doi: 10.2147/IJN.S104686

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© 2016 Gong et al. This work is published and licensed by Dove Medical Press Limited

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Hysteresis loop and T₂ relaxivity.

Notes: The hysteresis loop of MnFe₂O₄ NPs (A) showed that the magnetization rose nonlinearly with the increase of applied magnetic field and no remaining net magnetization in the absence of an external field, indicating that the MnFe₂O₄ NPs are superparamagnetic at 300 K. The MnFe₂O₄ NPs saturation magnetization was 68.2 emu/g (A). The linear fitting of concentration and 1/T₂ showed that the r₂ of PEG-b-PCL-MnFe₂O₄ NMs was 281.7 mM⁻¹ s⁻¹, which was ~4.2 times higher than that of TMAH-MnFe₂O₄ NPs (67.5 mM⁻¹ s⁻¹) (B).

Abbreviations: NMs, nanomicelles; NPs, nanoparticles; PEG-b-PCL, polyethylene glycol-block-poly(ε-caprolactone); r₂, transverse relaxivity; T₂, transverse relaxation time; TMAH, tetramethylammonium hydroxide.