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. 2016 Jul 4;12(3):1849–1853. doi: 10.3892/ol.2016.4810

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Copyright: © Zhang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 2. — Clinical Significance of CHKA expression in lung adenocarcinoma. (A) Lung adenocarcinoma patients were divided into a CHKA ‘high’ group (whose fold-change of relative expression was higher than the median) and ‘low’ group (whose fold-change of relative expression was lower than the median), and the overall survival rates of the 119 lung adenocarcinoma patients were compared between the CHKA ‘high’ group and the CHKA ‘low’ group. (B) Multivariate analysis of hazard ratios for overall survival of lung adenocarcinoma patients in tissue microarray. (C) Comparison of CHKA expression between lung adenocarcinoma patients whose differentiation status is poor or well. *P<0.05. Patients with poor differentiation exhibited higher CHKA expression than those with well-differentiated tumors. Cum, cumulative; CHKA, choline kinase α; HR, hazard ratio; CI, confidence interval; IHC, immunohistochemistry.