Table I.
Rat body weight in the various groups.
| Body weight | ||||
|---|---|---|---|---|
| Group | Day 0 (A) | Day 7 | Day 126 (B) | Gain (B - A) |
| Sham control | 181.63±5.48 | 207.75±3.92 | 283.13±13.05 | 101.50±12.81 |
| OVX control | 182.25±4.89 | 227.63±6.82a | 337.88±25.95a | 155.63±22.03a |
| Alendronate | 178.75±10.59 | 225.25±16.15b | 318.38±37.75 | 139.63±31.37a |
| Polycan | ||||
| 31.25 mg/kg | 176.75±11.42 | 223.10±18.02b | 329.88±41.27b | 153.13±33.36a |
| 62.5 mg/kg | 178.25±4.65 | 227.88±8.63a | 338.25±22.93a | 160.00±21.73a |
| 125 mg/kg | 177.75±6.45 | 221.63±9.46a | 333.00±32.26a | 125.25±30.41 |
Data are presented as the mean ± standard deviation of 8 rats. All rats were fasted overnight prior to the first treatment and 126 days following the initial treatment.
a
P<0.01
b
P<0.05 vs. sham control group. OVX, ovariectomized.