Table II.
Alterations in serum biochemistry.
| Group | Osteocalcin (ng/ml) | bALP (U/l) | Ca (mg/dl) | P (mg/dl) |
|---|---|---|---|---|
| Sham control | 1.349±0.185 | 1.425±0.238 | 9.338±0.774 | 6.650±0.960 |
| OVX control | 2.031±0.205a | 0.963±0.160a | 8.400±0.288a | 5.570±0.289a |
| Alendronate | 1.621±0.276b | 1.000±0.273a | 8.738±0.667 | 5.286±0.576a |
| Polycan | ||||
| 31.25 mg/kg | 1.908±0.086a | 1.213±0.181c | 8.863±0.555c | 5.595±0.452a |
| 62.5 mg/kg | 1.801±0.141a,c | 1.238±0.220b | 8.963±0.504c | 6.028±0.339c |
| 125 mg/kg | 1.760±0.167a,b | 1.300±0.141b | 9.013±0.344b | 6.044±0.417 |
Data are presented as the mean ± standard deviation of 8 rats.
a
P<0.01 vs. sham control group.
b
P<0.01
c
P<0.05 vs. OVX control group. OVX, ovariectomized; bALP, bone-specific alkaline phosphatase; Ca, calcium; P, phosphorus.