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. 2016 Jun 27;12(3):1251–1262. doi: 10.3892/etm.2016.3485

Table IV.

Alterations in bone mineral contents.

Polycan-treated groups

Bone Sham control OVX control Alendronate 31.25 mg/kg 62.5 mg/kg 125 mg/kg
Femur
  Ca mg/g bone 170.86±13.75 95.82±17.78a 120.95±12.40a,b 106.05±14.02c 125.12±9.03a,b 138.07±16.11a,b
  P mg/g bone 98.71±7.56 57.29±11.04a 73.60±13.18a,b 63.19±9.20c 76.48±11.47a,d 83.30±10.28c,d
  Ca/P ratio 1.74±0.16 1.70±0.34 1.69±0.34 1.70±0.28 1.67±0.29 1.68±0.29
Tibia
  Ca mg/g bone 196.13±9.74 103.82±15.02a 133.37±21.61a,d 110.14±14.66c 128.77±10.45a,d 140.72±15.00a,d
  P mg/g bone 99.66±11.83 52.67±7.66a 67.93±7.47a,d 55.54±6.04c 67.11±6.52a,d 70.00±7.12a,d
  Ca/P ratio 1.99±0.22 1.99±0.31 1.99±0.42 2.00±0.31 1.93±0.17 2.03±0.28
L4
  Ca mg/g bone 210.14±8.35a 124.41±12.48a 138.50±9.19a 138.10±13.87c 146.84±16.78a,b 155.79±11.09a,d
  P mg/g bone 113.50±13.77a 66.91±8.53a 74.12±7.24a 75.61±12.46c 78.77±10.05a,b 83.25±6.81a,d
  Ca/P ratio 1.87±0.23 1.90±0.45 1.88±0.20 1.87±0.38 1.88±0.23 1.88±0.16

Data are presented as the mean ± standard deviation of 8 rats.

a

P<0.01

c

P<0.05 vs. sham control group.

b

P<0.05

d

P<0.01 vs. OVX control group. OVX, ovariectomized; L4, 4th lumbar vertebrae.