Table II.
Univariate analysis.
| Parameters | Risk ratio | 95% confidence interval | P-value |
|---|---|---|---|
| Age at surgery (years) | |||
| ≤65 | 1 | ||
| >65 | 1.958 | 0.754–5.085 | 0.1677 |
| Gender | |||
| Male | 1 | ||
| Female | 1.379 | 0.532–3.577 | 0.5085 |
| Primary tumor | |||
| T1 | 1 | ||
| T2-4 | 10.870 | 2.481–47.619 | 0.0016 |
| Lymph node metastasis | |||
| N0 | 1 | ||
| N-positive | 41.667 | 5.435–41.667 | 0.0003 |
| Lymphatic invasion | |||
| Negative | 1 | ||
| Positive | 13.158 | 1.739–100.00 | 0.0125 |
| Vein invasion | |||
| Negative | 1 | ||
| Positive | 25.000 | 3.289–200.00 | 0.0019 |
| Differentiation status | |||
| Differentiated | 1 | ||
| Undifferentiated | 3.039 | 1.172–7.874 | 0.0223 |
| Immunostaining for NICD | |||
| Negative | 1 | ||
| Positive | 3.937 | 1.131–13.70 | 0.0312 |
NICD, NOTCH1 intracellular cytoplasmic domain.