Table III.
Multivariate analysis including NICD.
| Parameters | Risk ratio | 95% confidence interval | P-value |
|---|---|---|---|
| Primary tumor | |||
| T1 | 1 | ||
| T2-4 | 0.371 | 0.0528–2.618 | 0.3204 |
| Lymph node metastasis | |||
| N0 | 1 | ||
| N-positive | 27.778 | 2.632–333.33 | 0.0056 |
| Lymphatic invasion | |||
| Negative | 1 | ||
| Positive | 0.924 | 0.104–8.197 | 0.9435 |
| Vein invasion | |||
| Negative | 1 | ||
| Positive | 8.403 | 0.827–83.333 | 0.0719 |
| Differentiation status | |||
| Differentiated | 1 | ||
| Undifferentiated | 2.933 | 0.946–9.091 | 0.0623 |
| Immunostaining for NICD | |||
| Positive | 1 | ||
| Negative | 2.0747 | 0.451–9.524 | 0.3486 |
NICD, NOTCH1 intracellular cytoplasmic domain.