Table 2. Univariate Predictors of the First Appropriate Implantable Cardioverter-Defibrillator Therapy After Generator Replacement.

Risk Factor	HR	95% CI	P Value
Left ventricular ejection fraction (per 10% decrement)	1.48	1.16–1.89	0.002
NYHA functional class (per increase in NYHA class of 1)	1.72	1.18–2.45	0.005
QRS duration (per increment of 10 ms)	1.06	0.99–1.12	0.08
Stroke or transient ischemic attack	1.78	0.99–3.21	0.055
Hemoglobin (per decrement of 1 g/dL)	1.18	1.04–1.35	0.011
Estimated glomerular filtration rate (per decrement of 10 mL/min 1.73 m2)	1.12	1.02–1.23	0.02
Blood urea nitrogen (per increment of 10 mg/dL)	1.14	1.03–1.26	0.010
Serum sodium (per decrement of 10 mEq/L)	2.18	0.97–4.90	0.060

CI indicates confidence interval; HR, hazard ratio; and NYHA, New York Heart Association.